Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3973667 | 0.89 | IDO1 (0.48) | TSHRLMNAPTGS1GAAIDO1 | |
| SCHEMBL7086574 | 0.86 | LMNA (0.48) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL2451731 | 0.85 | MAOB (0.43) | LMNAPTGS1SLC6A2PTGS2SLC6A3 | |
| SCHEMBL1907545 | 0.85 | MAOB (0.43) | LMNACYP1A2PTGS1CYP2C19PTGS2 | |
| SCHEMBL6796911 | 0.85 | MAOB (0.44) | LMNAMAOBMAPTL3MBTL1MAPK1 | |
| SCHEMBL7284886 | 0.85 | HSD17B10 (0.44) | LMNASMN1; SMN2 | |
| SCHEMBL5790467 | 0.85 | TP53 (0.40) | TSHRLMNACYP1A2MAPTL3MBTL1 | |
| SCHEMBL8335296 | 0.83 | TSHR (0.47) | TSHRLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL7383564 | 0.83 | NR4A2 (0.57) | RAB9ASMN1; SMN2NR4A1NR4A2NR4A3 | |
| SCHEMBL2451926 | 0.82 | APP (0.49) | MAOBTDP1RAB9ASMN1; SMN2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3470 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130689-A1 | 2-FLUOROBIPHENYL-4-ACETIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 江苏普莱医药生物技术有限公司 | 2024-06-27 | — | — | WO | claimed |
| CN-115052860-B | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2024-06-21 | — | — | CN | claimed |
| US-20240132531-A1 | NOVEL GALACTOSIDE INHIBITOR OF GALECTINS | GALECTO BIOTECH AB (DK) | 2024-04-25 | — | — | US | claimed |
| CN-117624092-A | Method for preparing N-diaryl methyl substituted-2-amino furan compound | 湖南理工学院 | 2024-03-01 | — | — | CN | claimed |
| WO-2024042163-A1 | NOVEL SUBSTITUTED 2,3,4,9-TETRAHYDRO-1H-PYRIDO[3,4-B]INDOLE CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2024-02-29 | — | — | WO | claimed |
| CN-113549018-B | Protein kinase inhibitor and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2024-02-27 | — | — | CN | claimed |
| WO-2024010762-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2024-01-11 | — | — | WO | claimed |
| CN-117209558-A | Use of Mpro protein inhibitors in medicaments for the treatment of novel coronavirus infections | 北京大学深圳研究生院 | 2023-12-12 | — | — | CN | claimed |
| CN-117043156-A | Novel galectin inhibitors of galectins | 格莱克特生物技术公司 | 2023-11-10 | — | — | CN | claimed |
| EP-4267570-A1 | NOVEL GALACTOSIDE INHIBITOR OF GALECTINS | Galecto Biotech AB (DK) | 2023-11-01 | — | — | EP | claimed |
| EP-0009362-A1 | Heterocyclic derivatives of guanidine, their preparation and pharmaceutical formulations comprising them | McNeilab, Inc. (US) | 1980-04-02 | — | — | EP | claimed |
| US-4189500-A | VIRICIDES | STERLING DRUG INC. (US) | 1980-02-19 | — | — | US | claimed |
| EP-0007605-A1 | A process for inverting the configuration in optically active compounds and optically active intermediate compounds and their salts required therefor | CIBA-GEIGY AG (CH) | 1980-02-06 | — | — | EP | claimed |
| US-4185014-A | Kentenimine intermediates for 6α-methoxy-α-carboxy penicillins | BEECHAM GROUP LIMITED (GB) | 1980-01-22 | — | — | US | claimed |
| US-4181800-A | ANTIBIOTICS FROM SUBSTITUTED PERHYDRO-S-TRIAZINES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-01-01 | — | — | US | claimed |
| EP-0001238-A1 | Hydantoin derivatives, their synthesis, pharmaceutical formulations and intermediates in their preparation | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-04-04 | — | — | EP | claimed |
| US-4120689-A | POSTEMERGENT | MONSANTO COMPANY (US) | 1978-10-17 | — | — | US | claimed |
| US-3998958-A | Pyrrolidylidene, piperidylidene and hexahydroazepinylidene ureas as CNS depressants | MCNEIL LABORATORIES, INCORPORATED (US) | 1976-12-21 | — | — | US | claimed |
| US-3994724-A | SUBSTITUTED ANILINE PHOTOCONDUCTOR | SCOTT PAPER COMPANY (US) | 1976-11-30 | — | — | US | claimed |
| US-3969363-A | CARDIOVASCULAR DISORDERS | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-07-13 | — | — | US | claimed |