Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.82 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.82 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | RAB9A | P51151 | 6/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | NQO2 | P16083 | 1/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | IGF1R | P08069 | 1/20 | 0.59 |
| ▸ | IGF2R | P11717 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6797061 | 1.00 | ESR1 (0.82) | ESR1ESR2MAPTRAB9AALDH1A1 | |
| SCHEMBL8088202 | 0.93 | ESR1 (0.82) | ESR1ESR2MAPTRAB9AALDH1A1 | |
| SCHEMBL8088206 | 0.93 | ESR1 (0.82) | ESR1ESR2MAPTRAB9AALDH1A1 | |
| SCHEMBL11822838 | 0.92 | ALDH1A1 (0.74) | ESR1ESR2MAPTRAB9AALDH1A1 | |
| SCHEMBL11822854 | 0.92 | ALDH1A1 (0.74) | ESR1ESR2MAPTRAB9AALDH1A1 | |
| SCHEMBL901037 | 0.90 | ESR1 (1.00) | ESR1ESR2MAPTRAB9AALDH1A1 | |
| SCHEMBL901035 | 0.90 | ESR1 (1.00) | ESR1ESR2MAPTRAB9AALDH1A1 | |
| SCHEMBL347800 | 0.88 | RAB9A (0.69) | ESR1ESR2MAPTRAB9AALDH1A1 | |
| SCHEMBL247445 | 0.88 | RAB9A (0.69) | ESR1ESR2MAPTRAB9AALDH1A1 | |
| SCHEMBL247444 | 0.88 | RAB9A (0.69) | ESR1ESR2MAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |
| US-5736620-A | ENHANCED UNIDIRECTIONAL, MECHANICAL PROPERTIES AT LOWER TEMPERATURE | THE DOW CHEMICAL COMPANY (US) | 1998-04-07 | — | — | US | disclosed |
| US-5463091-A | Liquid crystals, polyepoxides | THE DOW CHEMICAL COMPANY (US) | 1995-10-31 | — | — | US | disclosed |