Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 3/20 | 0.42 |
| ▸ | MMP12 | P39900 | 3/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | MMP10 | P09238 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6777744 | 0.85 | TBXA2R (0.52) | PTAFRTBXA2RALOX5AP | |
| SCHEMBL9121396 | 0.74 | AGTR1 (0.58) | TBXA2RDRD2 | |
| SCHEMBL5837839 | 0.74 | SLC6A2 (0.52) | SLC6A2SLC6A4 | |
| SCHEMBL5837836 | 0.74 | SLC6A2 (0.52) | SLC6A2SLC6A4 | |
| SCHEMBL5837841 | 0.74 | SLC6A2 (0.52) | SLC6A2SLC6A4 | |
| SCHEMBL8391700 | 0.74 | PPARG (0.54) | TBXA2RDRD2 | |
| SCHEMBL8411049 | 0.74 | USP2 (0.55) | TBXA2RALOX5AP | |
| SCHEMBL6797316 | 0.74 | TBXA2R (0.42) | PTAFRTP53KDM4ELMNATBXA2R | |
| SCHEMBL9422538 | 0.73 | AGTR1 (0.50) | — | |
| SCHEMBL9039784 | 0.73 | PPARG (0.46) | MMP7MMP12MMP3MMP10MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716849-B1 | ISCHEMIC BRAIN DISORDERS; NEUROPROTECTANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-04-06 | — | — | US | disclosed |