Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 4/20 | 0.42 |
| ▸ | PTAFR | P25105 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6777744 | 0.75 | TBXA2R (0.52) | TBXA2RPTAFR | |
| SCHEMBL5838256 | 0.74 | CES2 (0.32) | LMNACYP2C9 | |
| SCHEMBL6797313 | 0.74 | PTAFR (0.43) | TBXA2RPTAFRLMNATP53NOD1 | |
| SCHEMBL9422539 | 0.73 | AGTR1 (0.51) | — | |
| SCHEMBL5838310 | 0.71 | ALDH1A1 (0.41) | — | |
| SCHEMBL28989060 | 0.69 | AGTR1 (0.67) | TBXA2RLMNANOD1CYP1A2CYP2C9 | |
| SCHEMBL5838998 | 0.69 | SMN1; SMN2 (0.48) | LMNASMN1; SMN2KDM4E | |
| SCHEMBL1169953 | 0.68 | LMNA (0.70) | TBXA2RLMNATP53SMN1; SMN2NOD1 | |
| SCHEMBL4088570 | 0.68 | TP53 (0.71) | TBXA2RLMNATP53SMN1; SMN2NOD1 | |
| SCHEMBL4097969 | 0.66 | NOD1 (0.71) | TBXA2RLMNATP53NOD1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716849-B1 | ISCHEMIC BRAIN DISORDERS; NEUROPROTECTANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-04-06 | — | — | US | disclosed |