Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP10 | P09238 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9042213 | 0.91 | PPARG (0.47) | PPARGAGTR1AGTR2TBXA2RDRD2 | |
| SCHEMBL9040419 | 0.90 | HDAC1 (0.52) | PPARGAGTR1AGTR2TBXA2RDRD2 | |
| SCHEMBL9041469 | 0.89 | PPARG (0.52) | PPARGAGTR1AGTR2TBXA2RSMN1; SMN2 | |
| SCHEMBL9043352 | 0.88 | RAB9A (0.55) | PPARGAGTR1AGTR2TBXA2RLMNA | |
| SCHEMBL9043441 | 0.88 | TP53 (0.56) | PPARGAGTR2TBXA2RDRD2LMNA | |
| SCHEMBL9040518 | 0.87 | MMP7 (0.53) | PPARGAGTR1AGTR2TBXA2RDRD2 | |
| SCHEMBL9042214 | 0.87 | HDAC1 (0.54) | PPARGAGTR1AGTR2LMNAMMP3 | |
| SCHEMBL9043476 | 0.86 | PPARG (0.65) | PPARGAGTR1AGTR2 | |
| SCHEMBL9042758 | 0.86 | POLB (0.59) | PPARGAGTR1AGTR2TBXA2RLMNA | |
| SCHEMBL9041081 | 0.86 | ALDH1A1 (0.51) | PPARGAGTR2TBXA2RDRD2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392317-B1 | Benzimidazoles, drugs containing these compounds and process for their preparation | THOMAE GMBH DR K (DE) | 1996-01-03 | — | — | EP | disclosed |
| EP-0392317-A2 | Benzimidazoles, drugs containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1990-10-17 | — | — | EP | disclosed |