Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL986690 | 0.93 | GPR119 (0.47) | GPR119OPRD1OPRK1OPRM1OPRL1 | |
| SCHEMBL15804318 | 0.88 | GPR119 (0.44) | GPR119OPRD1OPRK1OPRM1OPRL1 | |
| SCHEMBL31283650 | 0.86 | GPR119 (0.43) | GPR119OPRD1OPRK1OPRM1OPRL1 | |
| SCHEMBL7695449 | 0.80 | GPR119 (0.44) | GPR119OPRD1OPRK1OPRM1OPRL1 | |
| SCHEMBL3255190 | 0.79 | GPR119 (0.43) | GPR119OPRD1OPRK1GBA1SCD5 | |
| SCHEMBL2334586 | 0.79 | OPRM1 (0.47) | GPR119OPRM1OPRL1GBA1SCD5 | |
| SCHEMBL8347586 | 0.79 | TSHR (0.48) | GPR119OPRD1OPRK1GBA1SCD5 | |
| SCHEMBL3786845 | 0.78 | GPR119 (0.43) | GPR119GBA1SCD5TSHRALOX15 | |
| SCHEMBL8355728 | 0.78 | TSHR (0.45) | GPR119OPRD1OPRK1GBA1SCD5 | |
| SCHEMBL5467320 | 0.77 | SMN1; SMN2 (0.55) | OPRD1OPRK1OPRM1OPRL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040029887-A1 | Acetamides and benzamides that are useful in treating sexual dysfunction | ABBOTT LABORATORIES | 2004-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029887-A1 | Acetamides and benzamides that are useful in treating sexual dysfunction | CATSPER1, CYP19A1, PDE12 | GPR119 749/4885OPRD1 422/4885OPRK1 1724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.