SCHEMBL6799033

SCHEMBL6799033

COc1ccc(CCNC(=S)/C(=C\OCF)c2ccc3c(c2)CCCC3)cc1OC

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.49
KMT2A Q03164 4/20 0.48
MEN1 O00255 3/20 0.47
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.44
POLB P06746 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
HTT P42858 1/20 0.44
ALDH1A1 P00352 4/20 0.43
EPHX1 P07099 1/20 0.43
GAA P10253 1/20 0.43
MAPK1 P28482 1/20 0.42
HPGD P15428 1/20 0.42
ALOX12 P18054 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6799037 1.00 MAPT (0.49) MAPTKMT2AMEN1LMNATHRB
SCHEMBL6800929 0.90 ALDH1A1 (0.49) MAPTKMT2AMEN1LMNATHRB
SCHEMBL6800931 0.90 ALDH1A1 (0.49) MAPTKMT2AMEN1LMNATHRB
SCHEMBL6803726 0.82 ALDH1A1 (0.48) MAPTKMT2AMEN1LMNATHRB
SCHEMBL6803723 0.82 ALDH1A1 (0.48) MAPTKMT2AMEN1LMNATHRB
SCHEMBL6803491 0.78 ALDH1A1 (0.53) MAPTKMT2AMEN1LMNATHRB
SCHEMBL6798247 0.78 ALDH1A1 (0.53) MAPTKMT2AMEN1LMNATHRB
SCHEMBL6798918 0.78 ALDH1A1 (0.47) MAPTKMT2AMEN1LMNATHRB
SCHEMBL6798919 0.78 ALDH1A1 (0.47) MAPTKMT2AMEN1LMNATHRB
SCHEMBL6803466 0.77 LMNA (0.49) MAPTKMT2AMEN1LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6762321-B2 SUCH AS N-(2-(3,4-DIMETHOXYPHENYL)ETHYL)-3-DIFLUOROMETHOXY-2-(4 -METHYLPHENYL)ACRYLAMIDE; FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-07-13 US disclosed
US-20030195354-A1 Amide compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-10-16 US disclosed
EP-1295868-A1 AMIDE COMPOUNDS AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195354-A1 Amide compounds and use thereof CBR1, CBR3, NAT1 MAPT 3676/4885KMT2A 1480/4885MEN1 2217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.