Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.30 |
| ▸ | BAD | Q92934 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16742435 | 0.86 | NPC1 (0.35) | NPC1RAB9A | |
| SCHEMBL12488049 | 0.78 | TAAR1 (0.41) | MAPT | |
| SCHEMBL8072989 | 0.76 | ESR1 (0.32) | — | |
| SCHEMBL17514467 | 0.73 | — | — | |
| SCHEMBL5863299 | 0.72 | NFE2L2 (0.31) | NFE2L2 | |
| SCHEMBL17514868 | 0.71 | NISCH (0.38) | ALDH1A1NPC1RAB9A | |
| SCHEMBL7566027 | 0.71 | NPC1 (0.39) | ALDH1A1PTGS2NPC1RAB9A | |
| SCHEMBL9784274 | 0.71 | ACHE (0.41) | ALDH1A1PTGS2PTGS1NFE2L2MAPT | |
| SCHEMBL150096 | 0.70 | MAOB (0.32) | MAOBNFE2L2NPC1RAB9ABCL2L1 | |
| SCHEMBL9649202 | 0.69 | MEN1 (0.35) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | claimed |
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |
| EP-1370519-A1 | SYNTHETIC EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002068380-A1 | SYNTHETIC EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 2002-09-06 | — | — | WO | disclosed |