Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | YAP1 | P46937 | 3/20 | 0.38 |
| ▸ | TEAD4 | Q15561 | 3/20 | 0.38 |
| ▸ | UBE2M | P61081 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6186318 | 0.86 | SOAT1 (0.40) | UBE2MDCUN1D1SOAT2SOAT1 | |
| SCHEMBL6183409 | 0.84 | LPAR1 (0.43) | UBE2MDCUN1D1LPAR1SOAT2SOAT1 | |
| SCHEMBL6804805 | 0.83 | NMBR (0.38) | UBE2MDCUN1D1SOAT2SOAT1MEN1 | |
| SCHEMBL6807668 | 0.82 | UBE2M (0.38) | UBE2MDCUN1D1SOAT2SOAT1MEN1 | |
| SCHEMBL6182579 | 0.81 | SOAT1 (0.43) | UBE2MDCUN1D1SOAT2SOAT1MEN1 | |
| SCHEMBL6184262 | 0.80 | SOAT1 (0.40) | UBE2MDCUN1D1SOAT2SOAT1MEN1 | |
| SCHEMBL6803558 | 0.78 | UBE2M (0.39) | UBE2MDCUN1D1 | |
| SCHEMBL6202947 | 0.78 | MAPT (0.40) | LMNAUBE2MDCUN1D1SOAT2SOAT1 | |
| SCHEMBL6183734 | 0.77 | SOAT1 (0.38) | UBE2MDCUN1D1SOAT2SOAT1MEN1 | |
| SCHEMBL6803822 | 0.77 | SOAT2 (0.38) | HTTUBE2MDCUN1D1SOAT2SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | PFIZER INC. | 2004-04-01 | — | — | US | claimed |
| US-20040063643-A1 | Bombesin antagonists | PFIZER INC. | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | BRS3, NPSR1, GNRHR | LMNA 2660/4885ALDH1A1 3777/4885HTT 4402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.