SCHEMBL6803822

SCHEMBL6803822

CC(C)c1cccc(C(C)C)c1NC(=O)N(Cc1ccc(O)cc1)C(c1cccc(N(C)C)c1)C1CCCCC1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SOAT2 O75908 2/20 0.38
SOAT1 P35610 2/20 0.38
UBE2M P61081 1/20 0.38
DCUN1D1 Q96GG9 1/20 0.38
ACAT1 P24752 1/20 0.37
NMBR P28336 1/20 0.37
GRPR P30550 1/20 0.37
KDM4E B2RXH2 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
GFER P55789 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HSD17B10 Q99714 1/20 0.37
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6182579 0.84 SOAT1 (0.43) SOAT2SOAT1UBE2MDCUN1D1NMBR
SCHEMBL6183734 0.83 SOAT1 (0.38) SOAT2SOAT1UBE2MDCUN1D1NMBR
SCHEMBL6184262 0.82 SOAT1 (0.40) SOAT2SOAT1UBE2MDCUN1D1NMBR
SCHEMBL6183409 0.81 LPAR1 (0.43) SOAT2SOAT1UBE2MDCUN1D1NMBR
SCHEMBL6202947 0.81 MAPT (0.40) SOAT2SOAT1UBE2MDCUN1D1NMBR
SCHEMBL6186318 0.80 SOAT1 (0.40) SOAT2SOAT1UBE2MDCUN1D1NMBR
SCHEMBL6804805 0.79 NMBR (0.38) SOAT2SOAT1UBE2MDCUN1D1NMBR
SCHEMBL6807668 0.78 UBE2M (0.38) SOAT2SOAT1UBE2MDCUN1D1NMBR
SCHEMBL6799443 0.77 LMNA (0.39) SOAT2SOAT1UBE2MDCUN1D1HTT
SCHEMBL6803908 0.75 UBE2M (0.39) SOAT2SOAT1UBE2MDCUN1D1NMBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040063643-A1 Bombesin antagonists PFIZER INC. 2004-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063643-A1 Bombesin antagonists BRS3, NPSR1, GNRHR SOAT2 3379/4885SOAT1 3334/4885UBE2M 3897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.