Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIB | P23284 | 1/20 | 0.58 |
| ▸ | METAP1 | P53582 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6800097 | 0.92 | METAP1 (0.54) | PPIBMETAP1MAOBALDH1A1GAA | |
| SCHEMBL6801984 | 0.88 | SIGMAR1 (0.54) | PPIBMETAP1MAOBALDH1A1GAA | |
| SCHEMBL6796531 | 0.88 | PPIB (0.55) | PPIBMETAP1MAOBALDH1A1GAA | |
| SCHEMBL6795670 | 0.85 | CES2 (0.45) | PPIBMETAP1MAOBALDH1A1GAA | |
| SCHEMBL6794626 | 0.83 | METAP1 (0.51) | PPIBMETAP1MAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL11805867 | 0.82 | METAP1 (0.47) | PPIBMETAP1MAOBALDH1A1GAA | |
| SCHEMBL19737862 | 0.81 | METAP1 (0.51) | PPIBMETAP1MAOBALDH1A1GAA | |
| SCHEMBL23986655 | 0.81 | METAP1 (0.46) | PPIBMETAP1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL29993125 | 0.81 | METAP1 (0.46) | PPIBMETAP1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL6799152 | 0.81 | METAP1 (0.49) | PPIBMETAP1MAOBALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082642-A1 | Novel estrogen receptor ligands and method III | MERCK & CO., INC. | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082642-A1 | Novel estrogen receptor ligands and method III | ESRRA, ESRRB, FSHR | PPIB 1888/4885METAP1 4145/4885MAOB 1020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.