Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28750800 | 0.85 | NPC1 (0.46) | NPC1RAB9ADHODHCYP1A2CYP3A4 | |
| SCHEMBL6026603 | 0.84 | FABP4 (0.49) | NPC1RAB9ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6801051 | 0.83 | BCL2L1 (0.44) | NPC1RAB9ADHODHSMN1; SMN2KDM4E | |
| SCHEMBL6804369 | 0.79 | MYC (0.54) | NPC1RAB9ADHODHCYP3A4CYP2C9 | |
| SCHEMBL6803603 | 0.79 | RXRB (0.54) | DHODHCYP2C8CYP2C19KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL7907584 | 0.78 | MYC (0.53) | NPC1RAB9ADHODHCYP3A4CYP2C9 | |
| SCHEMBL27517441 | 0.75 | NPC1 (0.54) | NPC1RAB9ADHODHAURKATPX2 | |
| SCHEMBL10024251 | 0.75 | MCL1 (0.54) | NPC1RAB9ACYP2C9AURKATPX2 | |
| SCHEMBL10024263 | 0.75 | RXRB (0.58) | NPC1RAB9ASMN1; SMN2TSHRCASP1 | |
| SCHEMBL7924637 | 0.74 | TSHR (0.47) | CYP1A2CYP3A4CYP2C9SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | NPC1 40/4885RAB9A 4004/4885DHODH 4644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.