Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.68 |
| ▸ | CA2 | P00918 | 7/20 | 0.68 |
| ▸ | CA9 | Q16790 | 5/20 | 0.68 |
| ▸ | CA12 | O43570 | 4/20 | 0.64 |
| ▸ | PTPRF | P10586 | 1/20 | 0.58 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799239 | 0.87 | STS (0.61) | CA1CA2CA9CA12STS | |
| SCHEMBL3519559 | 0.82 | CA2 (1.00) | CA1CA2CA9CA12CA7 | |
| SCHEMBL4953680 | 0.82 | PTPRF (0.83) | PTPRFPTPN2PTPN1PTPN11MAPT | |
| SCHEMBL6801523 | 0.80 | CA2 (0.66) | CA1CA2CA9CA12MAPT | |
| SCHEMBL7454758 | 0.80 | CA2 (0.58) | CA1CA2CA9CA12STS | |
| SCHEMBL27565507 | 0.78 | PTPRF (0.71) | PTPRFPTPN2PTPN1PTPN11MAPT | |
| SCHEMBL14950713 | 0.78 | PTPRF (0.71) | PTPRFPTPN2PTPN1PTPN11MAPT | |
| SCHEMBL6255547 | 0.78 | PTPRF (0.71) | PTPRFPTPN2PTPN1PTPN11MAPT | |
| SCHEMBL7912544 | 0.78 | PTPRF (0.75) | PTPRFPTPN2PTPN1PTPN11MAPT | |
| SCHEMBL4667729 | 0.78 | CA2 (0.89) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |