Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.66 |
| ▸ | CA1 | P00915 | 8/20 | 0.66 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | BLM | P54132 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 7/20 | 0.54 |
| ▸ | CA12 | O43570 | 5/20 | 0.54 |
| ▸ | STS | P08842 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799239 | 0.92 | STS (0.61) | CA2CA1CA9CA12STS | |
| SCHEMBL7454758 | 0.84 | CA2 (0.58) | CA2CA1CA9CA12STS | |
| SCHEMBL6797084 | 0.81 | CA1 (0.67) | CA2CA1CA9CA12STS | |
| SCHEMBL5871758 | 0.80 | STS (0.81) | CA2CA1CA9CA12STS | |
| SCHEMBL6799583 | 0.80 | CA1 (0.68) | CA2CA1MAPTMEN1KMT2A | |
| SCHEMBL28436327 | 0.78 | CA2 (0.73) | CA2CA1CA9STS | |
| SCHEMBL10055010 | 0.78 | MAPT (0.80) | CA2CA1GAAMAPTMEN1 | |
| SCHEMBL6795311 | 0.78 | MAPT (0.80) | CA2CA1GAAMAPTMEN1 | |
| SCHEMBL28846873 | 0.76 | MAPT (0.70) | CA2CA1GAAMAPTMEN1 | |
| SCHEMBL5863587 | 0.76 | MAPT (0.70) | CA2CA1GAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |