Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 16/20 | 0.89 |
| ▸ | CA9 | Q16790 | 16/20 | 0.89 |
| ▸ | CA1 | P00915 | 15/20 | 0.89 |
| ▸ | CA12 | O43570 | 8/20 | 0.66 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.62 |
| ▸ | STS | P08842 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3519559 | 0.94 | CA2 (1.00) | CA2CA9CA1CA12CA14 | |
| SCHEMBL27565484 | 0.94 | CA2 (0.78) | CA2CA9CA1CA12CA14 | |
| SCHEMBL4667738 | 0.84 | CA2 (0.64) | CA2CA9CA1CA12CA14 | |
| Dinitrophenylene SCHEMBL27565505 | 0.83 | CA2 (0.66) | CA2CA9CA1CA12STS | |
| SCHEMBL4667304 | 0.82 | CA2 (0.65) | CA2CA9CA1CA12CA14 | |
| SCHEMBL27565486 | 0.80 | CA2 (0.72) | CA2CA9CA1CA12STS | |
| SCHEMBL866410 | 0.79 | CA1 (0.71) | CA2CA9CA1CA12CA14 | |
| SCHEMBL2236145 | 0.79 | CA2 (0.69) | CA2CA9CA1CA12CA14 | |
| SCHEMBL6806229 | 0.78 | SMN1; SMN2 (0.64) | CA2CA9CA1CA12CA14 | |
| SCHEMBL4667754 | 0.78 | STS (0.67) | CA2CA9CA1CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |