Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CCR9 | P51686 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1871602 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1MAPTTSHRL3MBTL1 | |
| SCHEMBL22175730 | 0.75 | KDM4E (0.35) | KDM4EALDH1A1MAPTTSHRL3MBTL1 | |
| SCHEMBL17824670 | 0.75 | OGA (0.39) | KDM4EALDH1A1MAPTTSHRL3MBTL1 | |
| SCHEMBL13946247 | 0.70 | NOS1 (0.41) | NOS1ALDH1A1OGAKDRPOLB | |
| SCHEMBL13285467 | 0.68 | ALDH1A1 (0.55) | NOS1KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL15061939 | 0.68 | ALDH1A1 (0.50) | NOS1KDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL22175658 | 0.68 | CDC7 (0.55) | KDM4EALDH1A1MAPTOGAPOLB | |
| SCHEMBL2305512 | 0.67 | ALDH1A1 (0.58) | NOS1KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL21477311 | 0.66 | ALDH1A1 (0.62) | NOS1KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL16636571 | 0.66 | ALDH1A1 (0.62) | KDM4EALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | NOS1 1463/4885KDM4E 2600/4885ALDH1A1 2901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.