Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 2/20 | 0.50 |
| ▸ | RXRB | P28702 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CD74 | P04233 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7150692 | 0.89 | KMO (0.50) | KMOKEAP1RXRARXRBKDM4E | |
| SCHEMBL8943468 | 0.85 | KMO (0.41) | KMOKEAP1RXRARXRBKDM4E | |
| SCHEMBL1510035 | 0.84 | KMO (0.59) | KMOKEAP1RXRARXRBKDM4E | |
| SCHEMBL10720633 | 0.83 | KMO (0.46) | KMOKEAP1RXRARXRBKDM4E | |
| SCHEMBL30725957 | 0.78 | KMO (0.86) | KMOKEAP1RXRARXRBCA12 | |
| SCHEMBL71238 | 0.78 | KMO (0.86) | KMOKEAP1RXRARXRBCA12 | |
| SCHEMBL29904709 | 0.78 | KMO (0.86) | KMOKEAP1RXRARXRBCA12 | |
| Hydrochloric Acid SCHEMBL4350309 | 0.76 | KMO (0.83) | KMOKEAP1RXRARXRBCA12 | |
| Water SCHEMBL10348973 | 0.76 | KMO (0.83) | KMOKEAP1RXRARXRBCA12 | |
| Hydrochloric Acid SCHEMBL21173951 | 0.76 | KMO (0.83) | KMOKEAP1RXRARXRBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | claimed |