SCHEMBL6800154

SCHEMBL6800154

CC(=O)Nc1cc(O)c(NS(=O)(=O)c2ccccc2)cc1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.59
ERBB2 P04626 1/20 0.57
HSP90AA1 P07900 1/20 0.57
HSP90AB1 P08238 1/20 0.57
GAA P10253 6/20 0.56
HSD17B10 Q99714 4/20 0.56
ALDH1A1 P00352 4/20 0.56
MEN1 O00255 3/20 0.56
ALOX15 P16050 3/20 0.56
HPGD P15428 1/20 0.56
TSHR P16473 3/20 0.52
LMNA P02545 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
GFER P55789 1/20 0.51
APOBEC3G Q9HC16 1/20 0.51
KDM4E B2RXH2 2/20 0.50
PIK3CD O00329 1/20 0.50
PIK3CG P48736 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6808841 0.87 ERBB2 (0.54) KMT2AERBB2HSP90AA1HSP90AB1GAA
SCHEMBL6806837 0.82 ALDH1A1 (0.66) KMT2AGAAHSD17B10ALDH1A1MEN1
SCHEMBL6808592 0.81 GAA (0.66) KMT2AERBB2HSP90AA1HSP90AB1GAA
SCHEMBL6802301 0.80 CA1 (0.50) KMT2AALDH1A1MEN1LMNAKDM4E
SCHEMBL14625517 0.80 KMT2A (0.60) KMT2AERBB2HSP90AA1HSP90AB1GAA
SCHEMBL2172266 0.80 KMT2A (0.57) KMT2AGAAHSD17B10ALDH1A1MEN1
SCHEMBL7806186 0.80 L3MBTL1 (0.49) KMT2AERBB2HSP90AA1HSP90AB1GAA
SCHEMBL6807579 0.80 HSD17B10 (0.57) KMT2AERBB2HSP90AA1HSP90AB1GAA
Hydrochloric Acid SCHEMBL7154981 0.79 L3MBTL1 (0.51) KMT2AERBB2HSP90AA1HSP90AB1GAA
SCHEMBL6805921 0.78 KMT2A (0.62) KMT2AERBB2HSP90AA1HSP90AB1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US claimed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US claimed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP claimed
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US disclosed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US disclosed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP disclosed