SCHEMBL6807579

SCHEMBL6807579

CC(=O)Nc1c(Cl)cc(NS(=O)(=O)c2ccccc2)c(O)c1Cl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.57
KMT2A Q03164 4/20 0.57
GAA P10253 3/20 0.57
ALOX15 P16050 3/20 0.57
ALDH1A1 P00352 2/20 0.57
MEN1 O00255 2/20 0.57
HPGD P15428 1/20 0.57
TSHR P16473 3/20 0.53
PIK3CD O00329 2/20 0.48
PIK3CG P48736 2/20 0.48
EP300 Q09472 1/20 0.48
PKM P14618 1/20 0.48
HTT P42858 1/20 0.48
ERBB2 P04626 1/20 0.48
HSP90AA1 P07900 1/20 0.48
HSP90AB1 P08238 1/20 0.48
LMNA P02545 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
KDM4E B2RXH2 2/20 0.46
PIK3C3 Q8NEB9 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6808046 0.88 KMT2A (0.55) HSD17B10KMT2AGAAALOX15ALDH1A1
SCHEMBL6801683 0.81 CA1 (0.38) KMT2AALDH1A1MEN1HPGDHTT
SCHEMBL14625517 0.81 KMT2A (0.60) HSD17B10KMT2AGAAALOX15ALDH1A1
SCHEMBL6806783 0.80 GAA (0.72) HSD17B10KMT2AGAAALOX15ALDH1A1
SCHEMBL6800154 0.80 KMT2A (0.59) HSD17B10KMT2AGAAALOX15ALDH1A1
SCHEMBL6803322 0.78 GAA (0.60) HSD17B10KMT2AGAAALOX15ALDH1A1
SCHEMBL13510406 0.76 EP300 (0.68) HSD17B10KMT2AGAAALOX15ALDH1A1
SCHEMBL7702173 0.76 GAA (0.69) HSD17B10KMT2AGAAALOX15ALDH1A1
SCHEMBL22203770 0.75 KMT2A (0.72) HSD17B10KMT2AGAAALOX15ALDH1A1
SCHEMBL10619794 0.75 GAA (0.82) HSD17B10KMT2AGAAALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US claimed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US claimed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP claimed
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US disclosed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US disclosed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP disclosed