Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29587274 | 0.82 | KMT2A (0.59) | FAAHTRPV1MGLLALDH1A1MEN1 | |
| SCHEMBL31715604 | 0.82 | MEN1 (0.64) | FAAHTRPV1MGLLALDH1A1MEN1 | |
| SCHEMBL599832 | 0.82 | CYP2C9 (0.67) | FAAHTRPV1MGLLMEN1KMT2A | |
| SCHEMBL29586128 | 0.81 | MGLL (0.48) | FAAHTRPV1MGLLALDH1A1MEN1 | |
| SCHEMBL213593 | 0.81 | MGLL (0.52) | FAAHTRPV1MGLLALDH1A1MEN1 | |
| SCHEMBL14907666 | 0.80 | MGLL (0.54) | FAAHTRPV1MGLLALDH1A1MEN1 | |
| SCHEMBL3757985 | 0.79 | CYP2C9 (0.60) | FAAHTRPV1MGLLALDH1A1MEN1 | |
| SCHEMBL6394617 | 0.79 | HTR2A (0.52) | FAAHTRPV1ALDH1A1MEN1KMT2A | |
| SCHEMBL16056377 | 0.79 | BCL9 (0.59) | FAAHTRPV1ALDH1A1MEN1KMT2A | |
| SCHEMBL31668309 | 0.79 | FAAH (0.45) | FAAHTRPV1MGLLALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6734182-B2 | SLEEP DISORDERS; EATING DISORDERS; SEXUAL DISORDERS; HYPOTENSIVE AGENTS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2004-05-11 | — | — | US | disclosed |
| US-20030013714-A1 | Aryl sulfonamides and sulfamide derivatives and uses thereof | SYNAPTIC PHARMACEUTICAL CORPORATION | 2003-01-16 | — | — | US | disclosed |
| US-6391877-B1 | EATING DISORDERS; SEXUAL DISORDERS; ANTIDEPRESSANTS; ANTIEPILEPTIC AGENTS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2002-05-21 | — | — | US | disclosed |
| US-6211241-B1 | ANTIDEPRESSANTS, SLEEP AND EATING DISORDERS AND ANTIEPILEPTIC AGENTS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2001-04-03 | — | — | US | disclosed |
| WO-1997019682-A1 | ARYL SULFONAMIDE AND SULFAMIDE DERIVATIVES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1997-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013714-A1 | Aryl sulfonamides and sulfamide derivatives and uses thereof | NPY5R, SSTR5, NPY2R | FAAH 184/4885TRPV1 1039/4885MGLL 3484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.