Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MGLL | Q99685 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | PTPRF | P10586 | 1/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599832 | 0.94 | CYP2C9 (0.67) | CYP2C9CYP2C19NPC1RAB9AMGLL | |
| SCHEMBL15231555 | 0.89 | CYP2C9 (0.55) | CYP2C9CYP2C19NPC1RAB9AMGLL | |
| SCHEMBL3765118 | 0.88 | MGLL (0.55) | CYP2C9CYP2C19NPC1RAB9AMGLL | |
| SCHEMBL20369602 | 0.86 | MGLL (0.60) | CYP2C9CYP2C19NPC1RAB9AMGLL | |
| SCHEMBL21410320 | 0.86 | MGLL (0.56) | CYP2C9CYP2C19NPC1RAB9AMGLL | |
| SCHEMBL21329860 | 0.86 | GAA (0.66) | NPC1RAB9AMGLLMEN1KMT2A | |
| SCHEMBL229908 | 0.86 | MGLL (0.56) | CYP2C9CYP2C19NPC1RAB9AMGLL | |
| SCHEMBL3275588 | 0.85 | ACKR3 (0.59) | CYP2C9CYP2C19RAB9AFFAR1PTPN1 | |
| SCHEMBL11408958 | 0.84 | CYP2C9 (0.62) | CYP2C9CYP2C19MGLLFFAR1FAAH | |
| SCHEMBL15567365 | 0.83 | MMP13 (0.67) | CYP2C9CYP2C19MGLLFAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298366-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2010-11-25 | — | — | US | disclosed |
| US-7790747-B2 | Chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090099205-A1 | Chemokine receptor binding compounds | GENZYME CORPORATION | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298366-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | CCR5, CXCR3, CCL5 | CYP2C9 4329/4885CYP2C19 4381/4885NPC1 542/4885 |
| US-20090099205-A1 | Chemokine receptor binding compounds | CCR5, CXCR3, CCL5 | CYP2C9 4329/4885CYP2C19 4381/4885NPC1 542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.