SCHEMBL6800580

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6799741	0.84	THRB (0.41)	ALDH1A1TSHRNPSR1POLBMAPT
	SCHEMBL7009095	0.82	TOP1 (0.39)	ALDH1A1TSHRNPSR1POLBALOX15
	SCHEMBL6801910	0.76	L3MBTL1 (0.37)	ALDH1A1TSHRNPSR1POLBMAPT
	SCHEMBL6801350	0.76	ALDH1A1 (0.40)	ALDH1A1TSHRALOX15TP53MAPT
	SCHEMBL6801629	0.75	MAPT (0.41)	ALDH1A1TSHRPIM1ALOX15TP53
	SCHEMBL6795932	0.73	ALDH1A1 (0.47)	ALDH1A1TSHRNPSR1ALOX15GRM4
	SCHEMBL6803072	0.73	KMT2A (0.39)	TP53MTORPRKDCPIK3CA
	SCHEMBL6803077	0.73	KMT2A (0.39)	TP53MTORPRKDCPIK3CA
	SCHEMBL6796311	0.73	ALDH1A1 (0.41)	ALDH1A1TSHRMAPT
	SCHEMBL6802031	0.72	TOP1 (0.44)	POLBTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.