Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28552521 | 1.00 | TDP1 (0.40) | TDP1HRH3LTA4HCHRNB2CHRNB4 | |
| SCHEMBL10748748 | 0.87 | HRH3 (0.43) | HRH3LTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL23872301 | 0.87 | HRH3 (0.43) | HRH3LTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7227482 | 0.87 | HRH3 (0.43) | HRH3LTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL23872300 | 0.84 | LTA4H (0.42) | HRH3LTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL15019591 | 0.78 | LTA4H (0.34) | HRH3LTA4HCARM1PRMT6PRMT8 | |
| SCHEMBL7710800 | 0.77 | HRH3 (0.37) | HRH3LTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7707987 | 0.77 | HRH3 (0.37) | HRH3LTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3801630 | 0.77 | HRH3 (0.37) | HRH3LTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL27553974 | 0.77 | HRH3 (0.37) | HRH3LTA4HCHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482944-B2 | BY DIRECT REACTION OF AN AMINE WITH AN ALPHA, GAMMA-DIHALOALKANE OR AN ALPHA, GAMMA-DIHALOALKENE; TERTIARY AMINOALKYLORGANOMETALLICS CAN BE MADE BY THEN REACTING THE TERT HALOALKYLAMINES WITH AN ALKALI METALS | FMC CORPORATION | 2002-11-19 | — | — | US | claimed |
| US-20010023305-A1 | Processes for preparing haloamines and tertiary aminoalkylorganometallic compounds | FMC CORPORATION | 2001-09-20 | — | — | US | claimed |
| US-6717014-B1 | REACTING AMINES WITH ALPHA-, OMEGA - DIHALOALKANES OR ALKENES; LOW COST; SAFE | FMC CORPORATION | 2004-04-06 | — | — | US | disclosed |
| US-6482944-B2 | BY DIRECT REACTION OF AN AMINE WITH AN ALPHA, GAMMA-DIHALOALKANE OR AN ALPHA, GAMMA-DIHALOALKENE; TERTIARY AMINOALKYLORGANOMETALLICS CAN BE MADE BY THEN REACTING THE TERT HALOALKYLAMINES WITH AN ALKALI METALS | FMC CORPORATION | 2002-11-19 | — | — | US | disclosed |
| US-20010023305-A1 | Processes for preparing haloamines and tertiary aminoalkylorganometallic compounds | FMC CORPORATION | 2001-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010023305-A1 | Processes for preparing haloamines and tertiary aminoalkylorganometallic compounds | HDHD5, DDC, DDT | TDP1 2287/4885HRH3 20/4885LTA4H 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.