Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | CTSB | P07858 | 1/20 | 0.58 |
| ▸ | CTSS | P25774 | 1/20 | 0.58 |
| ▸ | CTSK | P43235 | 1/20 | 0.58 |
| ▸ | PTPRB | P23467 | 10/20 | 0.57 |
| ▸ | TACR1 | P25103 | 2/20 | 0.57 |
| ▸ | F2 | P00734 | 3/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3478169 | 1.00 | CTSL (0.58) | CTSLCTSBCTSSCTSKPTPRB | |
| SCHEMBL3478166 | 1.00 | CTSL (0.58) | CTSLCTSBCTSSCTSKPTPRB | |
| SCHEMBL15627733 | 0.88 | CTSL (0.72) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL805151 | 0.88 | CTSL (0.72) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL13924735 | 0.86 | CTSL (0.66) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL10706786 | 0.83 | HDAC8 (0.68) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL6803112 | 0.83 | CTSL (0.56) | CTSLCTSBCTSSPTPRB | |
| SCHEMBL6768390 | 0.82 | ITGB3 (0.57) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL6803683 | 0.81 | CTSL (0.54) | CTSLCTSSCTSKPTPRB | |
| SCHEMBL6803693 | 0.81 | CTSL (0.54) | CTSLCTSSCTSKPTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074238-A1 | PHENETHYLAMINO SULFAMIC ACIDS | THE PROCTER & GAMBLE COMPANY (US) | 2004-09-02 | — | — | WO | claimed |
| US-20040167183-A1 | Phenethylamino sulfamic acids | THE PROCTER & GAMBLE COMPANY | 2004-08-26 | — | — | US | claimed |
| US-7769575-B2 | Three dimensional coordinates of HPTPbeta | Warner Chilcott, LLC (US) | 2010-08-03 | — | — | US | disclosed |
| US-7769575-B2 | Three dimensional coordinates of HPTPbeta | Warner Chilcott, LLC (US) | 2010-08-03 | — | — | US | disclosed |
| US-20100030487-A1 | THREE DIMENSIONAL COORDINATES OF HPTPbeta | Aerpio Pharmaceuticals, Inc. | 2010-02-04 | — | — | US | disclosed |
| US-20100030487-A1 | THREE DIMENSIONAL COORDINATES OF HPTPbeta | Aerpio Pharmaceuticals, Inc. | 2010-02-04 | — | — | US | disclosed |
| US-7507568-B2 | Three dimensional coordinates of HPTPbeta | THE PROCTOR & GAMBLE COMPANY (US) | 2009-03-24 | — | — | US | disclosed |
| US-7507568-B2 | Three dimensional coordinates of HPTPbeta | THE PROCTOR & GAMBLE COMPANY (US) | 2009-03-24 | — | — | US | disclosed |
| WO-2004074238-A1 | PHENETHYLAMINO SULFAMIC ACIDS | THE PROCTER & GAMBLE COMPANY (US) | 2004-09-02 | — | — | WO | disclosed |
| US-20040167183-A1 | Phenethylamino sulfamic acids | THE PROCTER & GAMBLE COMPANY | 2004-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167183-A1 | Phenethylamino sulfamic acids | PTPRM, PTPRS, PTPRE | CTSL 2677/4885CTSB 2219/4885CTSS 1861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.