Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MLYCD | O95822 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11139418 | 0.89 | HDAC8 (0.54) | ESR1ESR2ALDH1A1HPGDMLYCD | |
| SCHEMBL11142927 | 0.83 | HDAC8 (0.49) | ESR1ESR2ALDH1A1HPGDMLYCD | |
| SCHEMBL11139420 | 0.83 | ESR1 (0.58) | ESR1ESR2ALDH1A1HPGDMLYCD | |
| SCHEMBL18840276 | 0.82 | ALDH1A1 (0.67) | ESR1ESR2ALDH1A1HPGDMLYCD | |
| SCHEMBL6801988 | 0.80 | TSHR (0.58) | ALDH1A1HPGDMEN1KMT2AHTT | |
| SCHEMBL6421500 | 0.80 | ALDH1A1 (0.48) | ESR1ESR2ALDH1A1HPGDMLYCD | |
| SCHEMBL10926482 | 0.80 | ALDH1A1 (0.48) | ESR1ESR2ALDH1A1HPGDMLYCD | |
| SCHEMBL5702149 | 0.80 | ALDH1A1 (0.53) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL3656192 | 0.79 | ALDH1A1 (0.51) | ESR1ESR2ALDH1A1HPGDMEN1 | |
| SCHEMBL1006444 | 0.78 | HTT (0.71) | ALDH1A1HPGDMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1308297-C | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2007-04-04 | — | — | CN | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| CN-1360570-A | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2002-07-24 | — | — | CN | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |