Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NEK2 | P51955 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6807718 | 0.86 | NEK2 (0.44) | TDP1NEK2POLBKMT2AALDH1A1 | |
| SCHEMBL6805865 | 0.83 | TDP1 (0.41) | TDP1NEK2POLBKMT2AALDH1A1 | |
| SCHEMBL27446404 | 0.83 | TDP1 (0.40) | TDP1NEK2POLBKMT2AALDH1A1 | |
| SCHEMBL4640715 | 0.81 | KMT2A (0.39) | TDP1NEK2POLBKMT2AALDH1A1 | |
| SCHEMBL27474218 | 0.81 | KMT2A (0.39) | TDP1NEK2POLBKMT2AALDH1A1 | |
| SCHEMBL6805979 | 0.80 | CNR1 (0.41) | TDP1KMT2AALDH1A1MAPTCNR1 | |
| SCHEMBL27524223 | 0.79 | SMN1; SMN2 (0.40) | TDP1POLBKMT2AALDH1A1MAPT | |
| SCHEMBL6810273 | 0.79 | TDP1 (0.36) | TDP1POLBKMT2AALDH1A1MAPT | |
| SCHEMBL6807714 | 0.73 | ALDH1A1 (0.46) | NEK2POLBALDH1A1KDM4ECYP2C19 | |
| SCHEMBL5802620 | 0.73 | NEK2 (0.48) | NEK2POLBKMT2AALDH1A1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |