Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.38 |
| ▸ | ITGAV | P06756 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810547 | 0.91 | ITGB3 (0.40) | CNR1CNR2ITGB3ITGAVPREP | |
| SCHEMBL6811105 | 0.90 | CNR1 (0.44) | CNR1CNR2ITGB3ITGAVSMN1; SMN2 | |
| SCHEMBL6810562 | 0.87 | ITGB3 (0.41) | CNR1CNR2ITGB3ITGAVMAPT | |
| SCHEMBL6810273 | 0.84 | TDP1 (0.36) | CNR1CNR2ALDH1A1TDP1MAPT | |
| SCHEMBL6805849 | 0.83 | SYK (0.42) | SYKMAPTKLK7KLK5 | |
| SCHEMBL4640164 | 0.83 | ITGB3 (0.46) | CNR1CNR2ITGB3ITGAV | |
| SCHEMBL27524220 | 0.83 | ITGB3 (0.46) | CNR1CNR2ITGB3ITGAV | |
| SCHEMBL27524223 | 0.81 | SMN1; SMN2 (0.40) | CNR1CNR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6805722 | 0.81 | BTK (0.41) | SYKALDH1A1GAAMAPTKMT2A | |
| SCHEMBL6804912 | 0.80 | ITGB3 (0.45) | CNR1CNR2ITGB3ITGAVPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |