Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | FGB | P02675 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806744 | 0.69 | PPIB (0.37) | L3MBTL1ALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL10624432 | 0.65 | L3MBTL1 (0.55) | L3MBTL1CA1CA2CA7CA9 | |
| SCHEMBL6806743 | 0.65 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1MAPTPOLBPPARG | |
| SCHEMBL14939932 | 0.63 | L3MBTL1 (0.43) | L3MBTL1CA1CA2CA7CA9 | |
| SCHEMBL29498104 | 0.62 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1MAPTKDM4ECASP3 | |
| SCHEMBL1793005 | 0.62 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1MAPTKDM4ECASP3 | |
| SCHEMBL897309 | 0.62 | HTR5A (0.43) | ALDH1A1MAPTKDM4EOPRD1MEN1 | |
| Hydrochloric Acid SCHEMBL6600350 | 0.61 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL10711750 | 0.61 | CREBBP (0.53) | L3MBTL1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL20594366 | 0.61 | KDM4E (0.68) | L3MBTL1CA1CA2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082642-A1 | Novel estrogen receptor ligands and method III | MERCK & CO., INC. | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082642-A1 | Novel estrogen receptor ligands and method III | ESRRA, ESRRB, FSHR | L3MBTL1 3638/4885CA1 917/4885CA2 2206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.