Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.34 |
| ▸ | PPIB | P23284 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806744 | 0.89 | PPIB (0.37) | L3MBTL1NPSR1LMNAHTTHTR2A | |
| SCHEMBL6796508 | 0.76 | ALDH1A1 (0.46) | L3MBTL1NPSR1LMNAHTTHTR2A | |
| SCHEMBL29498104 | 0.73 | L3MBTL1 (0.46) | L3MBTL1NPSR1LMNAHTTHTR2A | |
| SCHEMBL1793005 | 0.73 | L3MBTL1 (0.46) | L3MBTL1NPSR1LMNAHTTHTR2A | |
| Hydrochloric Acid SCHEMBL6600350 | 0.71 | L3MBTL1 (0.45) | L3MBTL1NPSR1LMNAHTTHTR2A | |
| SCHEMBL31096283 | 0.71 | ALDH1A1 (0.44) | L3MBTL1NPSR1LMNAHTTCYP2D6 | |
| SCHEMBL8106287 | 0.71 | HTR2A (0.33) | HTR2ASIGMAR1CYP2D6 | |
| SCHEMBL132951 | 0.69 | ALDH1A1 (0.41) | L3MBTL1NPSR1LMNAHTTCYP2D6 | |
| SCHEMBL28221842 | 0.67 | SIGMAR1 (0.33) | LMNAHTR2ASIGMAR1CYP2D6 | |
| SCHEMBL6796515 | 0.67 | ALDH1A1 (0.56) | L3MBTL1NPSR1LMNAHTTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082642-A1 | Novel estrogen receptor ligands and method III | MERCK & CO., INC. | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082642-A1 | Novel estrogen receptor ligands and method III | ESRRA, ESRRB, FSHR | L3MBTL1 3638/4885NPSR1 119/4885LMNA 1190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.