Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.56 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15159900 | 0.90 | LRRK2 (0.60) | LRRK2TDO2ABCG2ABCB1CYP2C19 | |
| SCHEMBL395539 | 0.86 | CA2 (0.52) | KMT2AABCG2ABCB1DHODHSYK | |
| SCHEMBL28605262 | 0.80 | EGFR (0.45) | LRRK2TDO2ABCG2ABCB1DHODH | |
| SCHEMBL25546850 | 0.79 | MMP3 (0.56) | LRRK2ABCG2ABCB1DHODHCA1 | |
| SCHEMBL8329412 | 0.79 | CYP19A1 (0.52) | LRRK2TDO2ABCG2ABCB1DHODH | |
| SCHEMBL6800254 | 0.79 | CYP11B2 (0.59) | TDO2GAAABCG2ABCB1SYK | |
| SCHEMBL10567345 | 0.79 | ABCG2 (0.57) | LRRK2KMT2AABCG2CYP2C9CYP3A4 | |
| Isonicotinonitrile SCHEMBL151611 | 0.78 | — | — | |
| Isonicotinonitrile SCHEMBL12264099 | 0.78 | — | — | |
| Isonicotinonitrile SCHEMBL2015834 | 0.78 | HDAC8 (0.52) | GAAKMT2ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248426-B | Heterocyclic triarylamine compound and organic photoelectric device containing same | 浙江华显光电科技有限公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-113248426-A | Heterocyclic triarylamine compound and organic photoelectric device containing same | 浙江华显光电科技有限公司 | 2021-08-13 | — | — | CN | disclosed |
| CN-1308297-C | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2007-04-04 | — | — | CN | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| CN-1360570-A | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2002-07-24 | — | — | CN | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |