Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 6/20 | 0.50 |
| ▸ | DRD3 | P35462 | 5/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 4/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6807449 | 0.86 | MCHR1 (0.60) | MCHR1DRD2DRD3HTR7SIGMAR1 | |
| SCHEMBL5578409 | 0.85 | MCHR1 (0.71) | MCHR1DRD2DRD3HTR7HTR1A | |
| Hydrochloric Acid SCHEMBL5578294 | 0.84 | MCHR1 (0.70) | MCHR1DRD2DRD3HTR7HTR1A | |
| Trifluoroacetic Acid SCHEMBL6807608 | 0.82 | MCHR1 (0.62) | MCHR1DRD2DRD3HTR7HTR1A | |
| Trifluoroacetic Acid SCHEMBL6807470 | 0.82 | MCHR1 (0.57) | MCHR1DRD2DRD3HTR7HTR1A | |
| Trifluoroacetic Acid SCHEMBL6802111 | 0.82 | MCHR1 (0.64) | MCHR1DRD2DRD3HTR7HTR1A | |
| Trifluoroacetic Acid SCHEMBL6803305 | 0.81 | MCHR1 (0.63) | MCHR1DRD2DRD3HTR7SIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL6799476 | 0.81 | MCHR1 (0.60) | MCHR1DRD2DRD3HTR7HTR1A | |
| Trifluoroacetic Acid SCHEMBL6795675 | 0.80 | MCHR1 (0.59) | MCHR1DRD2DRD3HTR7HTR1A | |
| Trifluoroacetic Acid SCHEMBL6802636 | 0.79 | MCHR1 (0.58) | MCHR1DRD2DRD3HTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063699-A1 | Gpr14 antagonist | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-04-01 | — | — | US | disclosed |
| EP-1310490-A1 | GPR14 ANTAGONIST | Takeda Chemical Industries, Ltd. (JP) | 2003-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063699-A1 | Gpr14 antagonist | GPR142, GPR139, GPR4 | MCHR1 191/4885DRD2 329/4885DRD3 433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.