SCHEMBL2067538

SCHEMBL2067538

O=S(=O)(Nc1ccccc1NS(=O)(=O)c1ccccc1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.68
RECQL P46063 2/20 0.68
SMN1; SMN2 Q16637 1/20 0.68
IL1RN P18510 1/20 0.67
KEAP1 Q14145 1/20 0.67
ERAP1 Q9NZ08 1/20 0.67
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
PKM P14618 1/20 0.61
MAPT P10636 3/20 0.58
GAA P10253 1/20 0.58
MAPK1 P28482 1/20 0.58
HTT P42858 1/20 0.58
G6PD P11413 1/20 0.58
NFKBIA P25963 1/20 0.58
AGTR1 P30556 1/20 0.58
METAP2 P50579 1/20 0.58
METAP1 P53582 1/20 0.58
GLO1 Q04760 1/20 0.58
PAX8 Q06710 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23749791 0.89 ALDH1A1 (0.58) ALDH1A1RECQLSMN1; SMN2IL1RNKEAP1
SCHEMBL11785265 0.88 LMNA (0.77) ALDH1A1SMN1; SMN2KEAP1MEN1KMT2A
SCHEMBL4417172 0.87 ALDH1A1 (0.65) ALDH1A1RECQLSMN1; SMN2IL1RNKEAP1
SCHEMBL20568163 0.86 ALDH1A1 (0.54) ALDH1A1RECQLSMN1; SMN2IL1RNKEAP1
SCHEMBL13146416 0.85 ALDH1A1 (0.58) ALDH1A1RECQLSMN1; SMN2IL1RNKEAP1
SCHEMBL5731180 0.85 ALDH1A1 (0.58) ALDH1A1RECQLSMN1; SMN2IL1RNKEAP1
SCHEMBL6801689 0.85 RECQL (0.62) ALDH1A1RECQLSMN1; SMN2IL1RNKEAP1
SCHEMBL1195980 0.85 ALDH1A1 (0.58) ALDH1A1RECQLSMN1; SMN2IL1RNKEAP1
SCHEMBL3791578 0.85 TSHR (0.74) ALDH1A1RECQLSMN1; SMN2IL1RNKEAP1
SCHEMBL30102910 0.85 ALDH1A1 (0.74) ALDH1A1RECQLSMN1; SMN2KEAP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230288610-A1 WAVELENGTH SELECTIVE ABSORPTION FILTER AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-09-14 US disclosed
US-20230288610-A1 WAVELENGTH SELECTIVE ABSORPTION FILTER AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-09-14 US disclosed
EP-2998359-B1 METHOD FOR IMPROVING THE ELECTRICAL-INSULATING PROPERTY AND THE FOGGING RESISTANCE OF A POLYESTER RESIN COMPOSITION ADEKA CORP (JP) 2019-08-21 EP disclosed
US-9726932-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2017-08-08 US disclosed
US-9726932-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2017-08-08 US disclosed
US-9563075-B2 Method for manufacturing liquid crystal display device provided with front plate, and liquid crystal display device provided with front plate Konica Minolta, Inc. (JP) 2017-02-07 US disclosed
US-9563075-B2 Method for manufacturing liquid crystal display device provided with front plate, and liquid crystal display device provided with front plate Konica Minolta, Inc. (JP) 2017-02-07 US disclosed
US-20160231606-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2016-08-11 US disclosed
US-20160231606-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2016-08-11 US disclosed
US-9354356-B2 Polymer film, and optically-compensatory film, polarizer and liquid-crystal display device comprising the same FUJIFILM CORPORATION (JP) 2016-05-31 US disclosed
US-20070059458-A1 Cellulose acylate film, optically compensatory film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-03-15 US disclosed
EP-1239852-A2 BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS Arrow Therapeutics Limited (GB) 2002-09-18 EP disclosed
WO-2001028537-A2 BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS ARROW THERAPEUTICS LIMITED (GB) 2001-04-26 WO disclosed
WO-1999041756-A1 INTRINSICALLY CONDUCTIVE POLYMER BLENDS HAVING A LOW PERCOLATION THRESHOLD ZIPPERLING KESSLER & CO. (GMBH & CO.) (DE) 1999-08-19 WO disclosed
US-5908898-A ELECTRICALLY INSULATIVE THERMOPLASTIC MATRIX POLYMER DISPERSED THROUGH AN INTRINSICALLY CONDUCTIVE POLYMER SALT THAT IS INCOMPATIBLE WITH THE MATRIX POLYMER, A THERMOPLASTIC CONDUCTIVE PHASE POLYMER THAT IS PARTIALLY COMPATIBLE WITH MONSANTO COMPANY (US) 1999-06-01 US disclosed
WO-1999019391-A1 INTRINSICALLY CONDUCTIVE POLYMER/PLASTICIZER BLENDS WITH ENHANCED CONDUCTIVITY ZIPPERLING KESSLER & CO. (GMBH & CO.) (DE) 1999-04-22 WO disclosed
US-5871671-A Intrinsically conductive polymer/plasticizer blends with enhanced conductivity MONSANTO COMPANY (US) 1999-02-16 US disclosed
US-5264474-A Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds MTM AMERICAS INC. (US) 1993-11-23 US disclosed
US-4981890-A POLYHALOAROMATIC AND AROMATIC BIS-SULFONAMIDE ETHYL CORPORATION (US) 1991-01-01 US disclosed
US-4957958-A IMPROVED MELT FLOW ETHYL CORPORATION (US) 1990-09-18 US disclosed