SCHEMBL6801703

SCHEMBL6801703

COC(=O)Nc1c(Cl)cc(NS(C)(=O)=O)c(O)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
KDM4E B2RXH2 2/20 0.37
HSD17B10 Q99714 1/20 0.37
HPGD P15428 2/20 0.36
HTT P42858 1/20 0.36
CCR2 P41597 1/20 0.36
PGAM1 P18669 1/20 0.35
TSHR P16473 1/20 0.35
ACLY P53396 2/20 0.34
MCL1 Q07820 1/20 0.34
MAPT P10636 2/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
GFER P55789 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6801683 0.86 CA1 (0.38) ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL6808046 0.82 KMT2A (0.55) ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL6802561 0.77 SMN1; SMN2 (0.38) ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL6807239 0.74 GAA (0.43) ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL6806504 0.73 PIK3CD (0.41) ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E
Hydrochloric Acid SCHEMBL7160301 0.71 TSHR (0.32) TSHR
Hydrochloric Acid SCHEMBL7156647 0.71 MEN1 (0.30) SMN1; SMN2MEN1KMT2AHTTMAPT
SCHEMBL6940677 0.71 KMT2A (0.56) ALDH1A1MEN1KMT2AHTTMAPT
Hydrochloric Acid SCHEMBL6941980 0.70 KMT2A (0.58) ALDH1A1MEN1KMT2AHTTMAPT
SCHEMBL11545759 0.69 SMN1; SMN2 (0.41) ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US claimed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US claimed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP claimed
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US disclosed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US disclosed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP disclosed