SCHEMBL6806504

SCHEMBL6806504

CS(=O)(=O)Nc1cc(Cl)c(N)c(Cl)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.41
PIK3CA P42336 1/20 0.41
PIK3CB P42338 1/20 0.41
PIK3CG P48736 1/20 0.41
PGAM1 P18669 1/20 0.40
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
ADRB3 P13945 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
GAA P10253 1/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
EP300 Q09472 2/20 0.36
KAT2B Q92831 1/20 0.36
KAT8 Q9H7Z6 1/20 0.36
MCL1 Q07820 1/20 0.35
WDR5 P61964 1/20 0.35
NPC1 O15118 1/20 0.35
HSP90AA1 P07900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6807239 0.81 GAA (0.43) PIK3CDPIK3CAPIK3CBPIK3CGPGAM1
SCHEMBL6803322 0.77 GAA (0.60) PGAM1MEN1KMT2AALDH1A1HPGD
SCHEMBL6801683 0.75 CA1 (0.38) PIK3CAPIK3CBPGAM1MEN1KMT2A
SCHEMBL6806487 0.75 ADRA2A (0.45) PIK3CDPIK3CAPIK3CBPIK3CGMEN1
SCHEMBL6801703 0.73 ALDH1A1 (0.39) PGAM1MEN1KMT2AALDH1A1HPGD
SCHEMBL13510394 0.72 EP300 (0.62) PGAM1MEN1KMT2AALDH1A1HPGD
SCHEMBL12764248 0.71 CA1 (0.47) PIK3CDPIK3CAPIK3CBPIK3CGALDH1A1
SCHEMBL11603971 0.70 MCL1 (0.50) PIK3CDPIK3CAPIK3CBPIK3CGMEN1
SCHEMBL6812308 0.69 ALDH1A1 (0.48) MEN1KMT2AADRB3ALDH1A1HPGD
SCHEMBL16200088 0.69 ALDH1A1 (0.63) PIK3CDPIK3CAPIK3CBPIK3CGMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US claimed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US claimed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP claimed
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US disclosed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US disclosed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP disclosed