SCHEMBL6808046

SCHEMBL6808046

COC(=O)Nc1c(Cl)cc(NS(=O)(=O)c2ccccc2)c(O)c1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.55
GAA P10253 5/20 0.55
HSD17B10 Q99714 4/20 0.55
MEN1 O00255 4/20 0.55
ALOX15 P16050 3/20 0.55
ALDH1A1 P00352 2/20 0.55
HPGD P15428 1/20 0.55
TSHR P16473 2/20 0.51
KDM4E B2RXH2 2/20 0.49
EP300 Q09472 1/20 0.46
HTT P42858 2/20 0.46
PKM P14618 1/20 0.46
HSP90AA1 P07900 2/20 0.46
ERBB2 P04626 1/20 0.46
HSP90AB1 P08238 1/20 0.46
LMNA P02545 2/20 0.45
ACLY P53396 2/20 0.43
CCR2 P41597 1/20 0.43
CYTH2 Q99418 2/20 0.43
PGAM1 P18669 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6807579 0.88 HSD17B10 (0.57) KMT2AGAAHSD17B10MEN1ALOX15
SCHEMBL6801703 0.82 ALDH1A1 (0.39) KMT2AGAAHSD17B10MEN1ALDH1A1
SCHEMBL6808841 0.81 ERBB2 (0.54) KMT2AGAAHSD17B10MEN1ALOX15
SCHEMBL6806783 0.78 GAA (0.72) KMT2AGAAHSD17B10MEN1ALOX15
SCHEMBL6803322 0.76 GAA (0.60) KMT2AGAAHSD17B10MEN1ALOX15
SCHEMBL7702173 0.74 GAA (0.69) KMT2AGAAHSD17B10MEN1ALOX15
SCHEMBL10619794 0.73 GAA (0.82) KMT2AGAAHSD17B10MEN1ALOX15
SCHEMBL6806562 0.73 KMT2A (0.57) KMT2AGAAHSD17B10MEN1ALOX15
SCHEMBL13510376 0.72 EP300 (0.80) KMT2AGAAHSD17B10MEN1ALOX15
SCHEMBL5694590 0.72 ERBB2 (0.59) KMT2AGAAHSD17B10MEN1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US claimed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US claimed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP claimed
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US disclosed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US disclosed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP disclosed