SCHEMBL6801683

SCHEMBL6801683

CC(=O)Nc1c(Cl)cc(NS(C)(=O)=O)c(O)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
PIK3CA P42336 1/20 0.38
PIK3CB P42338 1/20 0.38
ALDH1A1 P00352 4/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37
PGAM1 P18669 1/20 0.37
PIK3C3 Q8NEB9 1/20 0.36
ADRB3 P13945 1/20 0.36
MCL1 Q07820 1/20 0.35
ATM Q13315 1/20 0.35
MAPT P10636 2/20 0.34
CCR2 P41597 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6801703 0.86 ALDH1A1 (0.39) ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL6807579 0.81 HSD17B10 (0.57) PIK3CAPIK3CBALDH1A1MEN1KMT2A
SCHEMBL6807239 0.76 GAA (0.43) PIK3CAPIK3CBALDH1A1MEN1KMT2A
SCHEMBL6802301 0.76 CA1 (0.50) CA1CA2CA9PIK3CAPIK3CB
SCHEMBL6806504 0.75 PIK3CD (0.41) CA1CA2CA9PIK3CAPIK3CB
SCHEMBL11149691 0.71 HSD17B10 (0.45) CA1CA2CA9ALDH1A1MEN1
SCHEMBL28358079 0.70 SMN1; SMN2 (0.45) CA1CA2CA9ALDH1A1MEN1
SCHEMBL6940422 0.70 ALDH1A1 (0.55) ALDH1A1MEN1KMT2AHTTMAPT
SCHEMBL6808046 0.69 KMT2A (0.55) ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E
Hydrochloric Acid SCHEMBL6941793 0.69 ALDH1A1 (0.57) ALDH1A1MEN1KMT2AHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US claimed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US claimed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP claimed
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US disclosed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US disclosed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP disclosed