Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20268120 | 0.88 | ALDH1A1 (0.43) | CYP1A2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3809367 | 0.84 | CYP1A2 (0.53) | CYP1A2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL165586 | 0.84 | CYP1A2 (0.53) | CYP1A2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27309405 | 0.82 | CYP1A2 (0.51) | CYP1A2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1407854 | 0.82 | CYP1A2 (0.51) | CYP1A2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL24520477 | 0.82 | CYP1A2 (0.51) | CYP1A2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27348210 | 0.82 | CYP1A2 (0.51) | CYP1A2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL269623 | 0.82 | CYP1A2 (0.51) | CYP1A2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL692975 | 0.81 | MAPK1 (0.43) | CYP1A2MEN1KMT2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL31378506 | 0.81 | CYP1A2 (0.50) | CYP1A2MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12509470-B2 | Antiviral heterocyclic compounds | ENANTA PHARMACEUTICALS, INC. (US) | 2025-12-30 | — | — | US | disclosed |
| US-12479842-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | UNIVERSITE DE MONTREAL (CA) | 2025-11-25 | — | — | US | disclosed |
| US-20250270207-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | UNIVERSITE DE MONTREAL (CA) | 2025-08-28 | — | — | US | disclosed |
| US-12139488-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | Université de Montréal (CA) | 2024-11-12 | — | — | US | disclosed |
| US-20240317747-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | Université de Montréal (CA) | 2024-09-26 | — | — | US | disclosed |
| US-12060353-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | Université de Montréal (CA) | 2024-08-13 | — | — | US | disclosed |
| US-20240217971-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | Université de Montréal (CA) | 2024-07-04 | — | — | US | disclosed |
| US-12006326-B2 | Antiviral heterocyclic compounds | ENANTA PHARMACEUTICALS, INC. (US) | 2024-06-11 | — | — | US | disclosed |
| US-20240140945-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | Université de Montréal (CA) | 2024-05-02 | — | — | US | disclosed |
| EP-4326719-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | Université de Montréal (CA) | 2024-02-28 | — | — | EP | disclosed |
| US-20090105208-A1 | Substituted Piperazines as CB1 Antagonists | SCHERING CORPORATION | 2009-04-23 | — | — | US | disclosed |
| WO-2009005646-A2 | SUBSTITUTED PIPERAZINES AS CB1 ANTAGONISTS | SCHERING CORPORATION (US) | 2009-01-08 | — | — | WO | disclosed |
| US-20040097508-A1 | Novel heterocyclically substituted amides, their preparation and use | ABBOTT GMBH & CO. KG (DE) | 2004-05-20 | — | — | US | disclosed |
| US-6630493-B1 | Inhibitors of capain enzymes useful for the treatment of ischemias of the heart, the kidney or of central nervous system (e.g. \"stroke\"), inflammations, muscular dystrophy, cataracts of the eyes, Alzheimer's disease etc. | BASF AKTIENGESELLSCHAFT (DE) | 2003-10-07 | — | — | US | disclosed |
| EP-0397365-B1 | Arylthiazolylimidazoles as 5HT3 Antagonists | PFIZER (US) | 1994-03-02 | — | — | EP | disclosed |
| US-5207820-A | Crop protection agents based on 1-aryl- or 1-hetarylimidazose carboxylic esters | BASF AKTIENGESELLSCHAFT (DE) | 1993-05-04 | — | — | US | disclosed |
| US-5043454-A | Antidotes used with herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1991-08-27 | — | — | US | disclosed |
| EP-0397365-A1 | Arylthiazolylimidazoles as 5HT3 Antagonists | PFIZER INC. (US) | 1990-11-14 | — | — | EP | disclosed |
| US-4914207-A | ANTIEMETICS | PFIZER INC. (US) | 1990-04-03 | — | — | US | disclosed |
| EP-0008596-A1 | Preparation of 4-hydroxymethyl-imidazole derivatives from the corresponding 4-imidazole carboxylic acid esters | DEVINTER Europe S.A. Société anonyme dite: (BE) | 1980-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270207-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | BRAF, NRAS, KRAS | CYP1A2 2314/4885MEN1 1789/4885KMT2A 2292/4885 |
| US-20040097508-A1 | Novel heterocyclically substituted amides, their preparation and use | CAPN1, CAPNS1, CAPN2 | CYP1A2 2635/4885MEN1 4075/4885KMT2A 4109/4885 |
| US-20240140945-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | BRAF, NRAS, KRAS | CYP1A2 2314/4885MEN1 1789/4885KMT2A 2292/4885 |
| US-12509470-B2 | Antiviral heterocyclic compounds | NR3C1, ZC3HAV1, HAVCR2 | CYP1A2 2797/4885MEN1 2420/4885KMT2A 2895/4885 |
| US-20240317747-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | BRAF, NRAS, KRAS | CYP1A2 2314/4885MEN1 1789/4885KMT2A 2292/4885 |
| US-12139488-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | BRAF, NRAS, KRAS | CYP1A2 2314/4885MEN1 1789/4885KMT2A 2292/4885 |
| US-12060353-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | BRAF, NRAS, KRAS | CYP1A2 2314/4885MEN1 1789/4885KMT2A 2292/4885 |
| US-20090105208-A1 | Substituted Piperazines as CB1 Antagonists | CNR1, CNR2, GPR119 | CYP1A2 475/4885MEN1 2811/4885KMT2A 1954/4885 |
| US-12479842-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | BRAF, NRAS, DPYD | CYP1A2 2263/4885MEN1 1888/4885KMT2A 2305/4885 |
| US-12006326-B2 | Antiviral heterocyclic compounds | ACE, HPRT1, ACE2 | CYP1A2 1080/4885MEN1 1038/4885KMT2A 2570/4885 |
| US-20240217971-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | BRAF, NRAS, DPYD | CYP1A2 2263/4885MEN1 1888/4885KMT2A 2305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.