Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EBP | Q15125 | 2/20 | 0.36 |
| ▸ | DHCR7 | Q9UBM7 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810634 | 0.84 | SMN1; SMN2 (0.41) | POLBSMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL14335735 | 0.82 | ALDH1A1 (0.32) | ALDH1A1MAPT | |
| SCHEMBL4459107 | 0.81 | HPGD (0.31) | HRH3SMN1; SMN2NPSR1ALDH1A1HTT | |
| SCHEMBL16592326 | 0.80 | — | — | |
| SCHEMBL16585705 | 0.79 | — | — | |
| SCHEMBL8950283 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2NPSR1ALDH1A1MAPTKMT2A | |
| SCHEMBL16592299 | 0.77 | — | — | |
| SCHEMBL7888667 | 0.76 | HSP90AA1 (0.34) | SMN1; SMN2NPSR1GAAALDH1A1MAPT | |
| SCHEMBL14405457 | 0.73 | LMNA (0.32) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL14405344 | 0.73 | MAPT (0.35) | GAAALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577629-B1 | NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS | CIBA GEIGY AG (CH) | 1996-06-26 | — | — | EP | claimed |
| WO-1992016510-A1 | NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS | CIBA-GEIGY AG (CH) | 1992-10-01 | — | — | WO | claimed |
| US-20040198797-A1 | Process for the preparation of herbicidal derivatives | MAETZKE THOMAS (CH) | 2004-10-07 | — | — | US | disclosed |
| EP-1183317-B1 | PROCESS FOR THE PREPARATION OF HERBICIDAL DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-09-17 | — | — | EP | disclosed |
| EP-0577629-B1 | NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS | CIBA GEIGY AG (CH) | 1996-06-26 | — | — | EP | disclosed |
| WO-1996011574-A1 | HERBICIDAL COMPOSITIONS | NOVARTIS AG (CH) | 1996-04-25 | — | — | WO | disclosed |
| US-5506193-A | Herbicidally, acaricidally and insecticidally active pyrazolidine compounds | CIBA-GEIGY CORPORATION (US) | 1996-04-09 | — | — | US | disclosed |
| US-5494890-A | FOR CONTROLLING WEEDS, INSECTS, MITES | CIBA-GEIGY CORPORATION (US) | 1996-02-27 | — | — | US | disclosed |
| EP-0577629-A1 | NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS. | CIBA GEIGY AG (CH) | 1994-01-12 | — | — | EP | disclosed |
| WO-1992016510-A1 | NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS | CIBA-GEIGY AG (CH) | 1992-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198797-A1 | Process for the preparation of herbicidal derivatives | CBR3, CBR1, CYC1 | HRH3 1448/4885POLB 3543/4885SMN1; SMN2 2256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.