SCHEMBL6802272

SCHEMBL6802272

Cc1ccc(NS(C)(=O)=O)c(O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B2 P37059 1/20 0.56
EP300 Q09472 1/20 0.51
KAT2B Q92831 1/20 0.51
KAT8 Q9H7Z6 1/20 0.51
CXCR2 P25025 2/20 0.46
KMT2A Q03164 4/20 0.45
GAA P10253 3/20 0.45
LMNA P02545 2/20 0.45
ADRA2A P08913 2/20 0.45
ADRA2B P18089 2/20 0.45
ADRA2C P18825 2/20 0.45
ADRA1A P35348 2/20 0.45
NPC1 O15118 1/20 0.45
TRPA1 O75762 1/20 0.45
MEN1 O00255 3/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
G6PD P11413 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28535495 0.85 HSD17B2 (0.56) HSD17B2EP300KAT2BKAT8CXCR2
SCHEMBL13393229 0.85 ADRA2A (0.57) HSD17B2EP300KAT2BKAT8GAA
SCHEMBL13303941 0.82 PTGS1 (0.47) EP300KAT2BKAT8LMNANPC1
SCHEMBL5181886 0.80 HSD17B2 (0.78) HSD17B2EP300KAT2BKAT8GAA
SCHEMBL2760280 0.80 FKBP1A (0.56) KMT2ANPC1MEN1ALDH1A1TDP1
SCHEMBL6573116 0.79 EP300 (0.50) EP300KAT2BKAT8KMT2AGAA
SCHEMBL11561858 0.78 FKBP1A (0.54) KMT2ANPC1MEN1ALDH1A1TDP1
Hydrochloric Acid SCHEMBL7160191 0.78 EP300 (0.49) EP300KAT2BKAT8KMT2AGAA
SCHEMBL6807990 0.78 HSD17B2 (0.69) HSD17B2EP300KAT2BKAT8KMT2A
SCHEMBL1290883 0.77 KMT2A (0.49) KMT2AGAALMNANPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US claimed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US claimed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP claimed
WO-2023288015-A1 M6PR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. (US) 2023-01-19 WO disclosed
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US disclosed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US disclosed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP disclosed