Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4215333 | 0.89 | — | — | |
| SCHEMBL1518987 | 0.72 | ADAM17 (0.32) | MT-CO2ALOX5MAPTPOLB | |
| Acetic Acid SCHEMBL1199912 | 0.72 | MMP1 (0.30) | — | |
| SCHEMBL1408376 | 0.70 | MAPT (0.35) | MAPTPOLB | |
| SCHEMBL6802326 | 0.69 | POLB (0.32) | POLB | |
| Bicarbonate SCHEMBL9560498 | 0.68 | MAPT (0.31) | MAPT | |
| SCHEMBL2239318 | 0.68 | — | — | |
| SCHEMBL1396610 | 0.67 | — | — | |
| SCHEMBL7255073 | 0.67 | — | — | |
| Oxalic Acid SCHEMBL9221351 | 0.67 | ACE (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014661-A1 | Periplasmic domain of an enterobacterium omp protein and its use as carrier or adjuvant | GOETSCH LILIANE (FR) | 2004-01-22 | — | — | US | disclosed |
| EP-1335935-A1 | PERIPLASMIC DOMAIN OF AN ENTEROBACTERIUM OMP PROTEIN AND ITS USE AS CARRIER OR ADJUVANT | PIERRE FABRE MEDICAMENT (FR) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002040518-A1 | PERIPLASMIC DOMAIN OF AN ENTEROBACTERIUM OMP PROTEIN AND ITS USE AS CARRIER OR ADJUVANT | PIERRE FABRE MEDICAMENT (FR) | 2002-05-23 | — | — | WO | disclosed |
| EP-1066054-A2 | USE OF ACTIVE P40 CONJUGATES FOR NASAL DELIVERY | PIERRE FABRE MEDICAMENT (FR) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999049892-A2 | USE OF ACTIVE P40 CONJUGATES FOR NASAL DELIVERY | PIERRE FABRE MEDICAMENT (FR) | 1999-10-07 | — | — | WO | disclosed |