SCHEMBL6802326

SCHEMBL6802326

CC(=O)ON1C(=O)CC(Br)C1=O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4326673 0.79 POLB (0.33) POLB
SCHEMBL3678842 0.79 MAPT (0.33) POLB
SCHEMBL12642095 0.78 ADAM17 (0.44) POLB
SCHEMBL16856451 0.78 POLB (0.32) POLB
SCHEMBL24311272 0.75 MMP2 (0.31) POLB
SCHEMBL3684074 0.75 CYP2C19 (0.41) POLB
SCHEMBL18067369 0.75 KMT2A (0.32) POLB
SCHEMBL25491686 0.75 POLB (0.32) POLB
SCHEMBL1109018 0.74 MMP2 (0.30) POLB
SCHEMBL24311271 0.74 MT-CO2 (0.50) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040014661-A1 Periplasmic domain of an enterobacterium omp protein and its use as carrier or adjuvant GOETSCH LILIANE (FR) 2004-01-22 US disclosed
EP-1335935-A1 PERIPLASMIC DOMAIN OF AN ENTEROBACTERIUM OMP PROTEIN AND ITS USE AS CARRIER OR ADJUVANT PIERRE FABRE MEDICAMENT (FR) 2003-08-20 EP disclosed
WO-2002040518-A1 PERIPLASMIC DOMAIN OF AN ENTEROBACTERIUM OMP PROTEIN AND ITS USE AS CARRIER OR ADJUVANT PIERRE FABRE MEDICAMENT (FR) 2002-05-23 WO disclosed
EP-1066054-A2 USE OF ACTIVE P40 CONJUGATES FOR NASAL DELIVERY PIERRE FABRE MEDICAMENT (FR) 2001-01-10 EP disclosed
WO-1999049892-A2 USE OF ACTIVE P40 CONJUGATES FOR NASAL DELIVERY PIERRE FABRE MEDICAMENT (FR) 1999-10-07 WO disclosed