SCHEMBL6803277

SCHEMBL6803277

CCOC(=O)CC1CCc2cc(NC(=O)c3ccc(C(=N)N)cc3F)ccc2O1

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 19/20 0.60
ITGA2B P08514 19/20 0.60
F2 P00734 1/20 0.39
F10 P00742 1/20 0.39
PLAU P00749 1/20 0.39
PLAT P00750 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6953858 0.99 ITGB3 (0.59) ITGB3ITGA2BF2F10PLAU
SCHEMBL6949560 0.90 ITGB3 (0.49) ITGB3ITGA2B
SCHEMBL6959161 0.90 ITGB3 (0.49) ITGB3ITGA2B
Hydrochloric Acid SCHEMBL6950979 0.89 ITGB3 (0.59) ITGB3ITGA2BF2F10PLAU
SCHEMBL7034481 0.88 ITGB3 (0.78) ITGB3ITGA2B
SCHEMBL6954534 0.88 ITGB3 (0.78) ITGB3ITGA2B
SCHEMBL7028235 0.88 ITGB3 (0.78) ITGB3ITGA2B
Hydrochloric Acid SCHEMBL6950435 0.88 ITGB3 (0.75) ITGB3ITGA2BPLAU
SCHEMBL6959422 0.87 ITGB3 (0.47) ITGB3ITGA2B
SCHEMBL6955908 0.85 ITGB3 (0.66) ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040014994-A1 Method for resolving chiral (2s) and (2r) chromanes ELI LILLY AND COMPANY 2004-01-22 US disclosed
EP-1292588-A1 METHODS FOR RESOLVING CHIRAL (2S) AND (2R) CHROMANES Eli Lilly & Company (US) 2003-03-19 EP disclosed
WO-2001094334-A1 METHODS FOR RESOLVING CHIRAL (2S) AND (2R) CHROMANES ELI LILLY & COMPANY (US) 2001-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014994-A1 Method for resolving chiral (2s) and (2r) chromanes TBXA2R, TBXAS1, SRR ITGB3 735/4885ITGA2B 2103/4885F2 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.