Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | FDPS | P14324 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | IGF1R | P08069 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7852893 | 0.90 | ALDH1A1 (0.53) | AMY1AMAPTGAAKDM4EKMT2A | |
| SCHEMBL29655344 | 0.86 | ALDH1A1 (0.69) | MAPTKDM4EKMT2ANPC1RAB9A | |
| SCHEMBL891274 | 0.86 | ALDH1A1 (0.69) | MAPTKDM4EKMT2ANPC1RAB9A | |
| SCHEMBL8925892 | 0.86 | ALDH1A1 (0.69) | MAPTKDM4EKMT2ANPC1RAB9A | |
| SCHEMBL356256 | 0.86 | ALDH1A1 (0.69) | MAPTKDM4EKMT2ANPC1RAB9A | |
| SCHEMBL721179 | 0.84 | ALDH1A1 (0.65) | MAPTGAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL356800 | 0.84 | FDPS (0.77) | MAPTFDPSNPC1RAB9AALDH1A1 | |
| SCHEMBL16955576 | 0.84 | MAPT (0.56) | AMY1AMAPTGAAKDM4EFDPS | |
| SCHEMBL6215450 | 0.84 | TRPA1 (0.56) | AMY1AMAPTGAAKDM4EFDPS | |
| SCHEMBL27539558 | 0.81 | FDPS (0.58) | MAPTKDM4EFDPSNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723743-B1 | TREATING PATIENT SUFFERING FROM RHEUMATOID ARTHRITIS, PSORIASIS, BRONCHIAL ASTHMA, ALZHEIMER'S DISEASE, MYOCARDIAL INFARCTION OR ATHEROSCLEROSIS | NEUROGEN CORPORATION | 2004-04-20 | — | — | US | claimed |