Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 10/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679146 | 0.91 | SCN9A (0.52) | SCN9AMCL1BCL2L1PLA2G7SCN5A | |
| SCHEMBL679917 | 0.87 | SCN9A (0.50) | SCN9APLA2G7SCN5A | |
| SCHEMBL680832 | 0.87 | PLA2G7 (0.55) | SCN9AMAPK14PLA2G7SCN5APTGDR2 | |
| SCHEMBL679849 | 0.84 | SCN9A (0.46) | SCN9AMCL1BCL2L1PLA2G7SCN5A | |
| SCHEMBL680151 | 0.83 | MAPK14 (0.61) | SCN9AMCL1BCL2L1MAPK14SCN5A | |
| SCHEMBL1690162 | 0.83 | SCN9A (0.46) | SCN9ASCN5AEZH2 | |
| SCHEMBL680209 | 0.82 | SCN9A (0.48) | SCN9APLA2G7SCN5A | |
| SCHEMBL680208 | 0.82 | TBXA2R (0.49) | SCN9APLA2G7SCN5AEZH2 | |
| SCHEMBL16319332 | 0.82 | SCN9A (0.61) | SCN9AMCL1BCL2L1PLA2G7SCN5A | |
| SCHEMBL679836 | 0.82 | SCN9A (0.51) | SCN9ASCN5AEZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593427-B1 | SULFONAMIDE DERIVATIVES AS NAV1.7 INHIBITORS FOR THE TREATMENT OF PAIN | PFIZER LTD (GB) | 2014-12-24 | — | — | EP | disclosed |
| US-20120010207-A1 | Chemical Compounds | PFIZER LIMITED (GB) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010207-A1 | Chemical Compounds | SCN1A, SCN1B, SCN7A | SCN9A 13/4885MCL1 2739/4885BCL2L1 3284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.