Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6807106 | 0.83 | F10 (0.53) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL6807557 | 0.81 | F10 (0.63) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL5163935 | 0.79 | F10 (0.55) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL5164789 | 0.79 | TSHR (0.48) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL5163957 | 0.77 | F10 (0.66) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL5166228 | 0.77 | F10 (0.53) | ALDH1A1RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL6157604 | 0.76 | F10 (0.47) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL6839785 | 0.76 | RAB9A (0.48) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL6807934 | 0.76 | MAPT (0.46) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL7086320 | 0.75 | ALDH1A1 (0.54) | ALDH1A1NPC1SMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1524072-A | Prenyl-containing derivatives and their use in the treatment of thromboembolic disorders or tumours | Ĭ��ר���ɷ�����˾ | 2004-08-25 | — | — | CN | claimed |
| US-20040092517-A1 | Phenyl derivatives and their use in the treatment of thromboembolic disorders or tumours | MERCK PATENT GMBH (DE) | 2004-05-13 | — | — | US | claimed |
| CN-1524072-A | Prenyl-containing derivatives and their use in the treatment of thromboembolic disorders or tumours | Ĭ��ר���ɷ�����˾ | 2004-08-25 | — | — | CN | disclosed |
| US-20040092517-A1 | Phenyl derivatives and their use in the treatment of thromboembolic disorders or tumours | MERCK PATENT GMBH (DE) | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092517-A1 | Phenyl derivatives and their use in the treatment of thromboembolic disorders or tumours | RCOR3, F2, NCOR2 | ALDH1A1 3576/4885RAB9A 4524/4885NPC1 2490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.