Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 15/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.46 |
| ▸ | MLNR | O43193 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6802636 | 0.80 | MCHR1 (0.58) | MCHR1DRD2HTR2AACHEHTR1A | |
| Trifluoroacetic Acid SCHEMBL6799996 | 0.79 | MCHR1 (0.56) | MCHR1ACHE | |
| Trifluoroacetic Acid SCHEMBL6807608 | 0.79 | MCHR1 (0.62) | MCHR1DRD2HTR2AACHEHTR1A | |
| Trifluoroacetic Acid SCHEMBL6807539 | 0.79 | MCHR1 (0.54) | MCHR1ACHELMNA | |
| Trifluoroacetic Acid SCHEMBL6796675 | 0.79 | MCHR1 (0.89) | MCHR1DRD2ACHE | |
| Trifluoroacetic Acid SCHEMBL6795286 | 0.79 | MCHR1 (0.60) | MCHR1ACHESLC6A2SLC6A4 | |
| Trifluoroacetic Acid SCHEMBL6806017 | 0.78 | MCHR1 (0.61) | MCHR1DRD2HTR2AACHELMNA | |
| Trifluoroacetic Acid SCHEMBL6800430 | 0.78 | MCHR1 (0.64) | MCHR1DRD2HTR2AACHEHTR1A | |
| Trifluoroacetic Acid SCHEMBL6799476 | 0.78 | MCHR1 (0.60) | MCHR1DRD2HTR2AACHEHTR1A | |
| Trifluoroacetic Acid SCHEMBL6799963 | 0.77 | MCHR1 (0.68) | MCHR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063699-A1 | Gpr14 antagonist | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-04-01 | — | — | US | disclosed |
| EP-1310490-A1 | GPR14 ANTAGONIST | Takeda Chemical Industries, Ltd. (JP) | 2003-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063699-A1 | Gpr14 antagonist | GPR142, GPR139, GPR4 | MCHR1 191/4885DRD2 329/4885HTR2A 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.