Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.60 |
| ▸ | CTSK | P43235 | 5/20 | 0.60 |
| ▸ | ACE | P12821 | 3/20 | 0.57 |
| ▸ | CTSB | P07858 | 3/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1790253 | 0.87 | ACE (0.70) | CTSSCTSKACECTSBCTSL | |
| SCHEMBL29400678 | 0.81 | CTSS (0.74) | CTSSCTSKACECTSBSCN9A | |
| SCHEMBL478595 | 0.81 | CTSS (0.74) | CTSSCTSKACECTSBSCN9A | |
| SCHEMBL1269412 | 0.81 | CTSS (0.74) | CTSSCTSKACECTSBSCN9A | |
| SCHEMBL478597 | 0.81 | CTSS (0.74) | CTSSCTSKACECTSBSCN9A | |
| SCHEMBL12909986 | 0.81 | CTSS (0.59) | CTSSCTSKACECTSBSCN9A | |
| SCHEMBL23125787 | 0.81 | CTSS (0.47) | CTSSCTSKACECTSBSCN9A | |
| SCHEMBL21447200 | 0.80 | CTSS (0.69) | CTSSCTSKACECTSBSCN9A | |
| SCHEMBL4282414 | 0.80 | CTSS (0.56) | CTSSCTSKACECTSBSCN9A | |
| SCHEMBL15876001 | 0.79 | CTSS (0.67) | CTSSCTSKACECTSBSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039792-A1 | DIHYDRO-FURAN-2-ONE DERIVATIVES, THEIR INTERMEDIATES AND METHODS OF MANUFACTURE | PFIZER PRODUCTS INC. (US) | 2004-05-13 | — | — | WO | disclosed |
| US-20040087797-A1 | Dihydro-furan-2-one derivatives, their intermediates and methods of manufacture | PFIZER INC | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087797-A1 | Dihydro-furan-2-one derivatives, their intermediates and methods of manufacture | CYP1B1, DHPS, CYP1A1 | CTSS 4354/4885CTSK 3903/4885ACE 1983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.