Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.70 |
| ▸ | CTSS | P25774 | 5/20 | 0.57 |
| ▸ | CTSK | P43235 | 5/20 | 0.57 |
| ▸ | CTSB | P07858 | 2/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.51 |
| ▸ | REN | P00797 | 2/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324257 | 0.91 | ACE (0.70) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL2106430 | 0.91 | ACE (0.63) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL6876021 | 0.91 | ACE (0.63) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL17695878 | 0.91 | ACE (0.63) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL6804174 | 0.87 | CTSS (0.60) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL7326335 | 0.87 | ACE (0.78) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL1791039 | 0.87 | ACE (0.78) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL12122453 | 0.85 | CTSS (0.64) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL1273042 | 0.85 | CTSS (0.64) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL18254890 | 0.84 | ACE (0.53) | ACECTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200172575-A1 | PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND | XDCEXPLORER (SHANGHAI) CO., LTD. (CN) | 2020-06-04 | — | — | US | disclosed |
| EP-3650464-A1 | PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND | XDCExplorer (Shanghai) Co., Ltd. (CN) | 2020-05-13 | — | — | EP | disclosed |
| WO-2019007383-A1 | PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND | 凯惠科技发展(上海)有限公司 | 2019-01-10 | — | — | WO | disclosed |
| US-7951834-B2 | Angiotensin I-converting enzyme (ACE) inhibitors | UNIVERSITY OF CAPE TOWN (ZA) | 2011-05-31 | — | — | US | disclosed |
| US-7951834-B2 | Angiotensin I-converting enzyme (ACE) inhibitors | UNIVERSITY OF CAPE TOWN (ZA) | 2011-05-31 | — | — | US | disclosed |
| US-7951834-B2 | Angiotensin I-converting enzyme (ACE) inhibitors | UNIVERSITY OF CAPE TOWN (ZA) | 2011-05-31 | — | — | US | disclosed |
| US-20090281160-A1 | Angiotensin I-converting enzyme (ace) inhibitors | ANGIODESIGN (UK) LIMITED (GB) | 2009-11-12 | — | — | US | disclosed |
| US-20090281160-A1 | Angiotensin I-converting enzyme (ace) inhibitors | ANGIODESIGN (UK) LIMITED (GB) | 2009-11-12 | — | — | US | disclosed |
| US-20090281160-A1 | Angiotensin I-converting enzyme (ace) inhibitors | ANGIODESIGN (UK) LIMITED (GB) | 2009-11-12 | — | — | US | disclosed |
| EP-1893633-A2 | ANGIOTENSIN I - CONVERTING ENZYME (ACE) INHIBITORS | University of Cape Town (ZA) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006126086-A2 | ANGIOTENSIN I - CONVERTING ENZYME (ACE) INHIBITORS | UNIVERSITY OF CAPE TOWN (ZA) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281160-A1 | Angiotensin I-converting enzyme (ace) inhibitors | ACE, ACE2, REN | ACE 1/4885CTSS 172/4885CTSK 148/4885 |
| US-20200172575-A1 | PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND | KISS1R, VIP, NPY1R | ACE 1694/4885CTSS 2804/4885CTSK 1962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.