Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 6/20 | 0.45 |
| ▸ | EIF2AK3 | Q9NZJ5 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | YES1 | P07947 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6800936 | 0.93 | EIF2AK3 (0.46) | RIPK1EIF2AK3MAPTNPC1TP53 | |
| SCHEMBL6667700 | 0.91 | SMO (0.49) | RIPK1EIF2AK3MAPTMTTPAPOB | |
| Hydrochloric Acid SCHEMBL6805924 | 0.90 | SMO (0.49) | RIPK1EIF2AK3MAPTMTTPAPOB | |
| SCHEMBL6800451 | 0.90 | EIF2AK3 (0.44) | RIPK1EIF2AK3MAPTNPC1TP53 | |
| SCHEMBL6805922 | 0.89 | RIPK1 (0.41) | RIPK1EIF2AK3MAPTNPC1TP53 | |
| SCHEMBL6803858 | 0.88 | SMO (0.52) | RIPK1EIF2AK3MAPTNPC1TP53 | |
| SCHEMBL6803373 | 0.88 | KDM4E (0.40) | MAPTNPC1RAB9ASMN1; SMN2MTTP | |
| SCHEMBL6802265 | 0.88 | RIPK1 (0.42) | RIPK1EIF2AK3MAPTNPC1TP53 | |
| SCHEMBL6803357 | 0.87 | EIF2AK3 (0.46) | RIPK1EIF2AK3MAPTNPC1TP53 | |
| Hydrochloric Acid SCHEMBL6804708 | 0.86 | EIF2AK3 (0.45) | RIPK1EIF2AK3MAPTNPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | RIPK1 3523/4885EIF2AK3 2638/4885MAPT 4047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.