Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 6/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.39 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6800936 | 0.95 | EIF2AK3 (0.46) | EIF2AK3RIPK1MAPTNPC1TP53 | |
| SCHEMBL6804308 | 0.90 | RIPK1 (0.45) | EIF2AK3RIPK1MAPTNPC1TP53 | |
| SCHEMBL6803357 | 0.89 | EIF2AK3 (0.46) | EIF2AK3RIPK1MAPTNPC1TP53 | |
| SCHEMBL6809686 | 0.89 | MAPT (0.40) | EIF2AK3RIPK1MAPTNPC1TP53 | |
| Hydrochloric Acid SCHEMBL6804708 | 0.88 | EIF2AK3 (0.45) | EIF2AK3RIPK1MAPTNPC1TP53 | |
| SCHEMBL6806302 | 0.88 | EIF2AK3 (0.48) | EIF2AK3MAPTNPC1TP53RAB9A | |
| Hydrochloric Acid SCHEMBL6808953 | 0.87 | EIF2AK3 (0.47) | EIF2AK3MAPTNPC1TP53RAB9A | |
| SCHEMBL6665119 | 0.87 | EIF2AK3 (0.44) | EIF2AK3RIPK1MAPTNPC1TP53 | |
| Hydrochloric Acid SCHEMBL6667512 | 0.86 | EIF2AK3 (0.43) | EIF2AK3RIPK1MAPTNPC1TP53 | |
| SCHEMBL6798695 | 0.84 | HTR2C (0.49) | EIF2AK3MAPTNPC1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | EIF2AK3 2638/4885RIPK1 3523/4885MAPT 4047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.